Pharmaceutical Enzymes

 Pharmaceutical Enzymes – Table of Contents

Volume 84 of the series “Drugs and the pharmaceutical sciences” (executive editor: J. Swarbrick)
1997/401 pages
ISBN: 9780824793753
This book can be ordered with Informa Healthcare Ltd.

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Bioavailability of pharmaceutical enzymes

  • Biopharmaceutical aspects of enzyme absorption
    Joseph Demeester
  • The endothelium monolayer: barrier to enzyme and drug delivery
    Felicia Antohe and Mark J. Poznansky

Tailoring of pharmaceutical enzymes

  • Enzyme-albumin conjugates: advantages and problems with targeting
    ,Mark J. Poznansky and Felicia Antohe
  • Acyl enzymes as prodrugs
    Fritz Markwardt
  • Molecular modeling of pharmaceutically important targets
    Gerrit Vriend, Dirk Hendriks and Simon Scharpé

Biochemical and pharmacological properties

  • The cysteine proteinases from the latex of Carica papaya L.
    Albert Lauwers and Philippe M. Dekeyser
  • Bromelain
    Greet Vanhoof and Walter Cooreman
  • Hyaluronidase
    Joseph Demeester and Koen P. Vercruysse
  • Pancreatic enzyme replacement
    Simon Scharpé, Wim Uyttenbroeck and Nele Samyn
  • I-asparaginase: an essential antineoplastic drug
    Volker Wahn
  • Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher disease
    Norman W. Barton and Roscoe O. BradyI
  • Deoxyribonuclease I
    Ingrid Demeester and Stefaan C. De Smedt
  • Therapeutic protein inhibitors of elastase
    David Farley, Bernard Faller and Hanspeter Nick

Standardization and methodology

  • Good standardization practices
    Albert Lauwers
  • Assays
    Joseph Demeester, Philippe M. Dekeyser, Nele Samyn, Ingrid Verhamme, Willy Sierens and Albert Lauwers