Research Output
Most research projects of the Lab of General Biochemistry and Physical Pharmacy are in close collaboration with universities from various European countries, which is facilitated through significant funding by Flemisch Agencies and the European Union. Our groups participated/participate in:
- DELNAM (H2020)
- COMPACT (Imi)
- NICHE (EU-Euronanomed II)
- NANOMED (EU ETN-Marie Curie Action)
- European Research Council (ERC)/NANOBUBBLE/Prof. Braeckmans, RESPIRNA/Prof. Raemdonck.
- Kom op tegen Kanker
- NanoCardio (Interreg)
- FWO
- VLAIO
- Koning BoudewijnStichting
2019 – S.C. De Smedt, R. Verbeke, H. Dewitte, I. Lentacker
Priority date: 12/04/2019
Application number: EP19168853.0
2018 – K. Braeckmans, S.C. De Smedt, J. Fraire
Priority date: 18/12/2018
Application number: EP18213548.3
2018 – S.C. De Smedt, K. Braeckmans, F. Sauvage
Priority: 08/10/2018
Application number: EP18199111.8
Entering PCT (not yet published)
2017 – K. Raemdonck, F. Joris, S. Stremersch, S. De Smedt
Priority: 19/01/2017
Application number: EP17152264.2
Entering PCT (not yet published)
2016 – K. Raemdonck, S. De Smedt
Priority: 24/11/2016
Application number: EP16200515.1
Entering PCT (not yet published)
2015 – A. Skirtach, J. Demeester, S. De Smedt, S. Stremersch, K. Raemdonck, K. Braeckmans
Entering PCT (not yet published)
2015 – K. Braeckmans, R. Xiong, S.K. Samal, S. De Smedt
Entering PCT
2014 – K. Braeckmans, S. De Smedt, J.Demeester, T. Coenye
Entering PCT (not yet published)
2012 – K. Braeckmans, H. Deschout, J. Demeester, S.C. De Smedt
Priority: 09/07/2010
Assigned in designated countries:
US9483440 (B2), EP2591333 (A1) under examination
Owner: UGent
2011 – K. Braeckmans, H. Deschout, K. Neyts, J. Demeester, S.C. De Smedt
Priority
Assigned in designated countries:
US8928875 (B2), EP2513628 (A1) under examination
Owner: UGent
2010 – K. Braeckmans, H. Deschout, J. Demeester and S.C. De Smedt
Priority: 9/7/2010
Assigned in designated countries:
US9483440 (B2), EP2591333 still under examination
Owner: UGent
2010 – S.C. De Smedt, J. Demeester, C. Huang, B. Lucas
Priority: 18/12/2009
Assigned in designated countries:
WO2011073442 (A1) Withdrawn
2006 – S.C. De Smedt, J. Demeester, B. De Geest and S. Derveaux
Priority: 20/10/2006
Assigned in designated countries:
EP1903337 (B1) withdrawn, JP5752881 (B2), US2010081215 (A1) still under examination (after ‘final rejection’)
Owner: Mycartis NV
2005 – S.C. De Smedt, J. Demeester and B. De Geest
Priority: 14/6/2005
Assigned in designated countries:
EP1733718 (A1)
2001 – N. Sanders, S. De Smedt and J. Demeester
Priorty: 13/4/2001
Assigned in designated countries:
US7432308 (B2)
2001 – B. Stubbe, S.C. De Smedt and J. Demeester
Priority: 21/12/2001
Assigned in designated countries:
EP1455832 (B1)
2001 – K. Braeckmans, S.C. De Smedt, J. Demeester, C. Roelant and M. Leblans
Priority: 19/10/2000
Assigned in designated countries:
ZA200303008 (B), US8735172 (B2), RU2285265 (C2), NO337637 (B1), JP4404547 (B2), CA2425775 (C), EP2275819
Owner: Mycartis NV
1999 – S.C.. De Smedt and J. Demeester, C. Roeland and R. Pauwels
Priority: 16/04/1999
Assigned in designated countries:
EP1173760 (B1), AU771517 (B2), CA2370315 (C), CN1271410 (C), US8967483 (B2) , ZA200108305 (B), RU2242746 (C2), JP4500455 (B2)
Owner: Mycartis NV
- Pharm. Gaëlle Houthaeve
- 2016-2021
- W. De Vos (promotor), K. Braeckmans (promotor)
- Pharm. Dawei Hua
- 2016-2021
- S. De Smedt (promotor), C. Huang (promotor), F. Sauvage, R. Xiong
- Pharm. Joke Deprez
- 2016-2021
- S. De Smedt (promotor) , P. Jacques (promotor), I. Lentacker (promotor)
- Pharm. Thys Van de Vyver
- 2016-2021
- K. Raemdonck (promotor), S. De Smedt (promotor)
- Pharm. Laurens Raes
- 2016-2021
- K. Braeckmans (promotor)
- Pharm. Jelter Van Hoeck
- 2016-2021
- K. Raemdonck (promotor)
- Sc. Aranit Harizaj
- 2016-2020
- K. Braeckmans (promotor) , I. Lentacker (promotor) and D. Poelman (promotor)
- Pharm. Roberta Guagliardo
- 2016-2020
- K.. Raemdonck (promotor), S. De Smedt (promotor)
- Pharm. Heyang Zhang
- 2016-2020
- K. Remaut (promotor), S. De Smedt (promotor)
- Pharm. Jing Liu
- 2016-2020
- K. Braeckmans (promotor), R. Xiong (promotor)
- Pharm. PJ. Merckx
- 2015-2020
- K. Raemdonck (promotor), S. De Smedt (promotor)
- Pharm. M. Shariati
- 2015-2020
- S. De Smedt (promotor), K. Remaut (promotor), W. Ceelen (promotor)
- Pharm. S. Roovers
- 2015-2019
- S. De Smedt (promotor), S. Lentacker (promotor)
- Pharm. E. Teirlinck
- 2014-2019
- K. Braeckmans (promotor), T. Coeneye (promotor)
- Pharm. J. Devoldere
- 2014-2019
- K. Remaut (promotor), S. De Smedt (promotor)
- Pharm. R. Verbeke
- 2013-2019
- S. De Smedt (promotor), H. Dewitte (promotor)
- Pharm. L. Vermeulen
- 2014-2018
- K. Remaut (promotor), K. Braeckmans (promotor)
- Pharm. K. Peynshaert
- 2013-2018
- K. Remaut (promotor), S. De Smedt (promotor)
- Pharm. E. Zagato
- 2012-2018
- K. Braeckmans (promotor), K. Neyt (promotor, K. Remaut (promotor)
- Pharm. R. Sobral Santos
- 2013-2017
- N. Azevedo (promotor), K. Braeckmans (promotor), S. De Smedt (promotor)
- Pharm. F. Joris
- 2013-2017
- S. De Smedt (promotor), K. Raemdonck (promotor)
- M.S. R. Xiong
- 2011 – 2017
- K. Braeckmans (promotor), S. De Smedt (promotor), A. Skirtach (co-promotor)
- Pharm. G. Dakwar
- 2011 – 2016
- K. Remaut (promotor), S. De Smedt (promotor), W. Ceelen (co-promotor)
- Pharm. S. Stremersch
- 2011 – 2016
- S. De Smedt (promotor), K. Raemdonck (promotor), K. Braeckmans (co-promotor)
- Pharm. L. Wayteck
- 2011 – 2016
- S. De Smedt (promotor), K. Raemdonck (promotor)
- Ir. K. Rombouts
- 2012 – 2016
- K. Braeckmans (promotor), K. Remaut (promotor)
- Pharm. I. De Cock
- 2011 – 2016
- S. De Smedt (promotor), I. Lentacker (co-promotor)
- Pharm. L. De Backer
- 2010-2015
- S. De Smedt (promotor), K. Raemdonck (co-promotor)
- Biotechnologist O. Andries
- 2010-2015
- N. Sanders (promotor), S. De Smedt (co-promotor), T. Kitada (co-promotor)
- Pharm. H. Dewitte
- 2010-2015
- S. De Smedt (promotor), K. Breckpot (promotor), I. Lentacker (co-promotor)
- Pharm. K. Forier
- 2009- 2013
- K. Braeckmans (promoter), J. Demeester (co-promoter), K. Raemdonck (co-promoter)
- Ir. T. Martens
- 2010-2014
- K. Braeckmans (promotor), S. De Smedt (co-promotor), K. Remaut (co-promotor)
- Pharm. B. Geers
- 2009-2013
- S.C. De Smedt (promotor), J. Demeester (promotor), I. Lentacker (co-promotor)
- Ir. H. Deschout
- 2007- 2012
- K. Braeckmans (promoter), K. Neyts (co-promoter), J. Demeester (co-promoter).
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- Pharm. M.L. De Temmerman
- 2007-2012
- S.C. De Smedt (promotor), J. Demeester (promotor), J. Rejman (co-promotor)
- Ir. N. Symens
- 2007-2012 Universiteit Gent
- S.C. De Smedt (promotor), K. Remaut (co-promotor), J. Rejman (co-promotor)
- Pharm. G. Tavernier
- 2007-2012
- S.C. De Smedt (promotor), J. Rejman (co-promotor), J. Adjaye (co-promotor)
- Master in Science W. De Haes
- 2007-2012 Universiteit Antwerpen
- G. Van Ham (promotor), S.C. De Smedt (co-promotor)
- Ir. C. Huang
- 2007-2011
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. D. Vercauteren
- 2006-2011
- S.C. De Smedt (co-promotor); K. Braeckmans (promotor)
- Pharm. B. Naeye
- 2006-2011
- S.C. De Smedt (promotor) J. Demeester (promotor), K. Raemdonck (co-promotor)
- Pharm. K. Raemdonck
- 2004-2009
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Pharm. K. Buyens
- 2004-2009
- S.C. De Smedt (promotor), N.N. Sanders (promotor)
- Pharm. I. Lentacker
- 2003-2009
- S.C. De Smedt (-promotor), N.N. Sanders (promotor), J. Demeester(copromotor)
- Pharm. F. Fayazpour
- 2003-2008
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. S. S. Derveaux
- 2003- 2008
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. S. De Koker
- 2003-2008 t
- S.C. De Smedt (co-promotor), N. Mertens (co-promotor) J. Grooten (promotor)
- Biotechnologist R. Vandenbroucke
- 2003-2008
- S.C. De Smedt (co-promotor), J. Demeester (promotor), N.N. Sanders (promotor)
- Ir. B. De Geest
- 2003 – 2006
- S.C. De Smedt (promotor), J. Demeester ( promotor)
- Gehonoreerd met de Andreas De Leenheer Prijs (2008) uitgereikt door de International Club of Flanders
- Biotechnologist L. Peeters
- 2003-2008
- S.C. De Smedt (promotor), N.N. Sanders (promotor), J. Demeester (co-promotor)
- Ir. T. Van Thienen
- 2002 – 2007
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Pharm. S. Van Tomme
- 2007
- S.C. De Smedt (promotor), W. Hennink (promotor)
- Pharm. K. Remaut
- 2001-2007
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Ir. B. Lucas
- 2000 – 2005
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Pharm. E. Van Rompaey
- 1998 – 2003
- S.C De Smedt (promotor), J. Demeester (promotor)
- Pharm. N. Sanders
- 1997-2001
- S.C De Smedt (promotor), J. Demeester (promotor)
- Gehonoreerd met de nationale prijs van het Belgisch Genootschap voor Farmaceutische Wetenschappen (2003) en de Leonardo Award (2002)
- Physicist K. Braeckmans
- 1999 -2004
- S.C. De Smedt (promotor), J. Demeester (promotor)
- Gehonoreerd met de “Young Biotechnology Researchers Award” (2005)
- Pharm. B. Stubbe
- 1999 – 2004
- S.C De Smedt (promotor), J. Demeester (promotor)
- Ir. T. Meyvis
- 1995-1999
- S.C De Smedt (co-promotor), J. Demeester (promotor)
Publications
Year: 2026
- Improving transport efficiency for large human cells for enabling accurate determination of cellular nanoparticle uptake via SC-ICP-TOF-MS
Mina Nikolić, Ana Lores Padín, Thibaut Van Acker, Tina Smets, Ilia Goemaere, Amin Ahmad, Kevin Braeckmans , Eduardo Bolea-Fernandez and Frank Vanhaecke. (2026) TALANTA. 297.
Year: 2025
- DNA damage-associated vesicle production in Stenotrophomonas maltophilia is mediated by a cryptic tailocin endolysin
Darshan Chandramowli, Jolien Vitse, Stephan Stremersch, Koen Raemdonck, Kevin Braeckmans and Bart Devreese. (2025) BIORXIV. - Impact of pneumatic tube transportation on the aggregation of monoclonal antibodies in clinical practice(2025) EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 204.
- Intrinsic differential scanning fluorimetry for protein stability assessment in microwell plates
(2025) MOLECULAR PHARMACEUTICS. 22(3). p.1697-1706 - Immunogenic cell death as interplay between physical anticancer modalities and immunotherapy
(2025) JOURNAL OF CONTROLLED RELEASE. 384. - Developing a single-cell ICP-TOF-MS method for photoporation studies : improving low transport efficiencies for large human cells
(2025) Plasma Spectrochemistry 2025, 20th European Winter Conference, Abstracts. - Photothermal nanofiber-mediated photoporation for gentle and efficient intracellular delivery of macromolecules(2025) NATURE PROTOCOLS.
- Gentle and efficient engineering of primary human NK cells by photoporation with polydopamine nanosensitizers
(2025) JOURNAL OF CONTROLLED RELEASE. 382.